Distinct influences of tandem repeats and retrotransposons on CENH3 nucleosome positioning
نویسندگان
چکیده
منابع مشابه
Nucleosome-positioning sequence repeats impact chromatin silencing in yeast minichromosomes.
Eukaryotic gene expression occurs in the context of structurally distinct chromosomal domains such as the relatively open, gene-rich, and transcriptionally active euchromatin and the condensed and gene-poor heterochromatin where its specific chromatin environment inhibits transcription. To study gene silencing by heterochromatin, we created a minichromosome reporter system where the gene silenc...
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Nucleosomes, the building blocks of chromatin, are responsible for DNA packaging in eukaryotic cell nuclei. They play a structural role in genome condensation, and influence transcription and replication. Properties of the DNA sequence, such as curvature and flexibility, direct the location of nucleosomes. DNA sequences that position nucleosomes have been identified and rules that govern their ...
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The formation and precise positioning of nucleosome in chromatin occupies a very important role of study in life process. Today, many researchers discover that the positioning where the location of a DNA sequence fragment wraps around a histone in genome is not random but regular. However, the positioning is closely relevant to the concrete sequence of core DNA. So in this paper, we analyzed th...
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ژورنال
عنوان ژورنال: Epigenetics & Chromatin
سال: 2011
ISSN: 1756-8935
DOI: 10.1186/1756-8935-4-3